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Invitrogen™ DNA Ligase III Polyclonal Antibody

Beskrivning
Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Mouse (92%), Rat (91%), Pig (94%), Rhesus Monkey (97%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100 kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97 kDa (beta form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
Specifikationer
Specifikationer
| Antigen | DNA Ligase III |
| Användningsområden | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Klassificering | Polyclonal |
| Koncentration | 0.81 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gen | LIG3 |
| Genaccessionsnr. | P49916 |
| Gene Alias | D11Wsu78e; DNA ligase (ATP) 3; DNA ligase 3; DNA ligase III; hypothetical protein; LIG2; LIG3; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 3; Unknown (protein for MGC:134139) |
| Gensymboler | LIG3 |
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