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Doxepin hydrochloride

Produktkod. 15494919
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Produktkod. 15494919 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer J62579.03
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Beskrivning

Potent H1-histamine receptor antagonist and a 5-HT receptor antagonist | CAS: 1229-29-4 | C19H22ClNO | 315.841 g/mol

It is a highly potent H1 histamine receptor antagonist (Kd = 310 pM) and tricyclic antidepressant that inhibits the reuptake of serotonin and norepinephrine and acts as an antagonist at histamine, serotonin, adrenergic, and muscarinic receptors with Ki values in the nanomolar range. Also binds to the H4 histamine receptor (pKi = 6.79). Used clinically to treat anxiety and depression.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water (100 mM), chloroform (1:2), alcohol (1:1), methanol, and DMSO.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 1229-29-4
Molekylformel C19H22ClNO
Molekylvikt (g/mol) 315.841
MDL-nummer MFCD00079135
InChI-nyckel MHNSPTUQQIYJOT-SJDTYFKWSA-N
Synonym doxepin hydrochloride, novoxapin, aponal, toruan, curatin, sinequan, zonalon, adapin, doxepine hydrochloride, novoxapin hydrochloride
PubChem CID 6419921
IUPAC-namn (3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride
LEDER CN(C)CCC=C1C2=CC=CC=C2COC3=CC=CC=C31.Cl

Specifikationer

Kemiskt namn eller material Doxepin hydrochloride
Smältpunkt 187°C to 189°C
Färg White
Kvantitet 1 g
UN-nummer UN2811
Merck Index 14,3435
Löslighetsinformation Soluble in water (100 mM),chloroform (1:2),alcohol (1:1),methanol,and DMSO.
Formel vikt 315.84
Fysisk form Powder

RUO – Research Use Only

Produkttitel
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