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Invitrogen™ EDG6 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA523221

Produktkod. 13277118

  • 4905.00 SEK / 100µg

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Beskrivning

Beskrivning

Immunogen sequence homology: 100% homologous in human; mouse/rat (95%).

EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the EDG6 (S1P4) receptor is the sphingosine 1-phosphate receptor-4 (S1P4).
TRUSTED_SUSTAINABILITY
Specifikationer

Specifikationer

EDG6
Polyclonal
Unconjugated
S1PR4
Edg6; EDG-6; Endothelial differentiation G-protein coupled receptor 6; endothelial differentiation G-protein-coupled receptor 6; endothelial differentiation, G protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6; LPC1; Lysophospholipid receptor C1; S1P receptor 4; S1P receptor Edg-6; S1P(4) receptor; S1p4; S1PR4; SLP4; sphingosine 1-phosphate receptor 4; Sphingosine 1-phosphate receptor Edg-6; sphingosine-1-phosphate receptor 4
Rabbit
Antigen affinity chromatography
RUO
13611, 8698
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1.0 mg/mL
PBS with 0.05% sodium azide
O95977, Q9Z0L1
S1PR4
A portion of amino acids 1-50 of human Sphingolipid Receptor Edg6/S1P4.
100 μg
Primary
Human, Mouse
Antibody
IgG
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