EEF1B2 Polyclonal Antibody, Invitrogen™

Description

Immunogen sequence: FGDLKSPAGL QVLNDYLADK SYIEGYVPSQ ADVAVFEAVS SPPPADLCHA LRWYNHIKSY EKEKASLPGV KKALGKYGPA DVEDTTGSGA TD Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.

EF-1 (elongation factor-1) is a multi-protein complex that is responsible forthe delivery of aminoacyl-tRNAs to the ribosome. The EF-1 protein complexis composed of four subunits: EF-1 α, EF-1 β, EF-1 δ and EF-1 γ. EF-1 β is a225 amino acid member of the EF-1 β/EF-1 δ protein family and contains oneGST C-terminal domain. Both EF-1 β and EF-1 δ stimulate the exchange ofGDP bound to EF-1 α to GTP. Phosphorylation of EF-1 β affects the GDP/GTP exchange rate. Alternative splicing events of the gene that encodes EF-1 β result in three transcript variants that differ only in the 5' UTR.