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Invitrogen™ Human EEF2K, GST Tag Recombinant Protein

Produktkod. 10046532
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10046532 10 μg 10µg
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For Research Use Only. All usage must comply with product instructions.
Produktkod. 10046532 Leverantör Invitrogen™ Leverantörsnummer PV4559
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Beräknad leverans: 09-11-2026
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For Research Use Only. All usage must comply with product instructions.

Beskrivning

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

EEF2K is a highly conserved Serine/Threoning kinase in the calmodulin signaling pathway whose activity is increased in cancers including breast cancer. EEF2K (eukaryotic elongation factor 2 kinase) is a threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Up activation, by a variety of upstream kinases including AMPK or TRPM7, EEF2K phosphorylates the elongation factor EEF2 at a single site. Then, EEF2K renders EEF2 unable to bind ribosomes and inactive - in turn, the rate of protein synthesis is reduced.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer O00418
Koncentration See Label
För användning med (applikation) Kinase Assay
Formulering 50mM tris with 0.02% Triton X-100, 50% glycerol, 2mM DTT, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
Gen-ID (Entrez) 29904
Molekylvikt (g/mol) 109.9 kDa
Namn Human EEF2K, GST Tag
pH-intervall 7.5
Reningsmetod Purified
Kvantitet 10 μg
Förvaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias C86191; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; calmodulin-dependent protein kinase III; EC 2.7.11.20; eEF-2 kinase; Eef2k; eEF-2K; EF2K; elongation factor 2 kinase; elongation factor-2 kinase; euk; eukaroytic elongation factor 2 kinase; eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; HSU93850; kinase eEF2K; SMEF2K
Vanligt namn EEF2K
Gensymbol EEF2K
KinaseFamily Alpha Kinase Family
Produkttyp Protein
Konjugera Unconjugated
Art Human
Rekombinant Recombinant
Protein Tag GST-tag
Sekvens Full length
Innehåll och lagring Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Analysinträde Biochemical phospho-specific activity (no antibody)
Kinase Group Ser⁄Thr Kinases: Atypical
Frakt skick Dry Ice
Systemkompatibilitet Zin-LYTE™
Målinträde EEF2K
Target Gene eukaryotic elongation factor-2 kinase
Uttryckssystem E. coli
Proteinfamilj Kinases & Inhibitors
Proteinform Recombinant, Full Length
Form Liquid
Protein subtyp Serine/Threonine Kinases
Forskningskategori Drug Discovery: Oncology, Signal Transduction
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