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EID1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11734-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16829013

  • 3248.87 SEK / 150µL
Estimated Shipment: 30-11-2021

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Description

Description

E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
Specifications

Specifications

EID1
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9DCR4, Q9Y6B2
21 kDa pRb associated protein, C15orf3, CRI1, EID 1, EID1, IRO45620, PNAS 22, PTD014, RBP21
Rabbit
IgG
150 μL
-20°C
Primary
23741, 58521
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
EID1
Liquid
Eid1
EID1 Fusion Protein Ag2336
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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