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EIF3E Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10899-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16827593

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
Specifications

Specifications

EIF3E
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P60228, P60229, Q641X8
eIF 3 p48, eIF3 p46, EIF3 P48, EIF3E, EIF3S6, INT6
Rabbit
IgG
20 μL
-20°C
Primary
103692906, 16341, 3646
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
EIF3E
Liquid
EIF3E
EIF3E Fusion Protein Ag1132
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Mouse, Human
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