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EIF3L Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | EIF3L |
---|---|
Concentration | 0.4 mg/mL |
Applications | Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16838593
|
Proteintech
11482-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 26-04-2024 Log in to see stock. |
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16828593
|
Proteintech
11482-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 26-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that lead to 80S ribosomal assembly and, ultimately, translation. The eukaryotic initiation factor-3 (eIF3) scaffolding structure is the largest of the eIF complexes and includes eIF3alpha, eIF3beta, eIF3delta, eIF3gamma, eIF3eta, eIF3epsilon, eIF3theta and eIF3zeta, all of which function to control the assembly of the 40S ribosomal subunit. Association of eIF3 proteins with the 40S ribosomal subunit stabilizes eIF2-GTP-Met-tRNAiMet complex association and mRNA binding, and promotes dissociation of 80S ribosomes into 40S and 60S subunits, thereby promoting the assembly of the pre-initiation complex. Overexpression of eIF3 proteins is common in several cancers, suggesting a role for eIF3 proteins in tumorigenesis.Specifications
EIF3L | |
Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q8QZY1, Q9Y262 | |
223691, 300069, 51386 | |
EIF3L Fusion Protein Ag1974 | |
Primary | |
-20°C | |
EIF3L |
0.4 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
EIF3EIP, EIF3L, EIF3S11, EIF3S6IP, HSPC021, HSPC025, MSTP005 | |
EIF3L | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |