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Invitrogen™ Silencer™ Human Epigenetics siRNA Library

The Silencer™ Human Epigenetics siRNA Library contains 1,560 Invitrogen™ Silencer siRNAs targeting 520 epigenetic enzymes, including those mediating epigenetic signaling through the acetylation and methylation of histones.

Brand:  Invitrogen™ A30086

Additional Details : Weight : 0.04000kg

Product Code. 15651852

  • 109000.00 SEK / 1 set
Estimated Shipment: 22-04-2024
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Description

Description

Epigenetic regulation of gene expression is proving to be a key regulator in the development and progression of a host of human diseases. The Silencer™ Human Epigenetics siRNA Library contains 1,560 Ambion™ Silencer siRNAs targeting 520 epigenetic enzymes, including those mediating epigenetic signaling through the acetylation and methylation of histones. The library was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC). Utilizing Ambion Silencer technology built on stringent bioinformatics to ensure high target specificity and siRNA potency, the Silencer Human Epigenetics siRNA Library is an ideal RNAi screening solution for focused and cost-effective epigenetic gene knockdown studies

Why use the Silencer Human Epigenetics siRNA Library?Together with careful bioinformatics selection of gene targets, Silencer siRNAs are optimized for design and high quality synthesis with guaranteed silencing. The Silencer Human Epigenetics siRNA Library contains our pre-designed and when available, validated siRNAs generated with maximum potency and specificity in mind so you can focus on data quality. All Silencer libraries are selected against the latest available databases and resources for up-to-date content. Full siRNA sequence information, as well as the exon targeted and each targeted gene's symbol, full name, aliases, RefSeq number, and Locus ID, plus results from any validation experiments performed using the included siRNAs is provided. Please contact us for the complete list of targets.Silencer siRNA libraries allow you to screen efficiently and maximize data outputInvitrogen Silencer siRNAs are designed with potency in mind to help ensure gene knockdown at minimum concentrations. This not only helps ensure less potential for off target effects and false positive data but also minimizes false negative outcomes of siRNA screening. The Silencer Human Epigenetics siRNA Library contains 0.25 nmol of each siRNA, sufficient for 100 transfections (at 25 nM siRNA, 100 μL transfection volume).
  • Comprehensive—Expedite the discovery of epigenetic regulation of gene expression with pre-defined Silencer Human Epigenetics siRNA Library
  • Reliable—Increase target screening accuracy with three individual siRNAs per gene target
  • Effective—Reduce off target impacts at low concentrations with proven Invitrogen Silencer siRNA design
  • Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
  • Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats
Specifications

Specifications

1563 total siRNAs targeting 521 genes plated onto 96-well plates (18 plates)
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Special Offers

Special Offers

For research use only. Not for use in diagnostic procedures