missing translation for 'onlineSavingsMsg'
Learn More

EOMES Monoclonal Antibody (Dan11mag), eBioscience™, Invitrogen™

Rat Monoclonal Antibody

1220.00 SEK - 3005.00 SEK

Specifications

Antigen EOMES
Clone Dan11mag
Concentration 0.5 mg/mL
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15207397
View Documents Promotion Details
Affymetrix eBioscience
14-4875-80
25 μg
1220.00 SEK
25µg
View alternative products
Save Up to 
»
Estimated Shipment: 09-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
15217397
View Documents Promotion Details
Affymetrix eBioscience
14-4875-82
100 μg
3005.00 SEK
100µg
View alternative products
Save Up to 
»
Estimated Shipment: 09-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: This Dan11mag antibody recognizes Eomesodermin (Eomes), also known as T-box brain 2 (TBR2). Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates. In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells. Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R. Applications Reported: This Dan11mag antibody has been reported for use in immunohistochemistry of formalin-fixed paraffin embedded tissue sections, intracellular staining followed by flow cytometric analysis, and western blotting. (Fluorochrome conjugated Dan11mag is recommended for use in intracellular flow cytometry.). Applications Tested: This Dan11mag antibody has been tested by intracellular staining followed by flow cytometric analysis of mouse splenocytes and/or western blotting at 5 μg/mL. This Dan11mag antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded mouse tissue using low pH antigen retrieval at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
Specifications

Specifications

EOMES
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Eomes
Primary
4° C
Eomes
Dan11mag
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rat
Mouse
O54839
13813
IgG2a κ
Affinity chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.