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EPHA6 Recombinant Human Protein

EPHA6 Recombinant Human Protein

Brand:  Invitrogen PV6337

Additional Details : Weight : 0.01000kg

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Product Code. 15458973

  • 2975.00 SEK / 10µg


Estimated Shipment date
from Supplier 28-12-2017
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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context. Recombinant human EPHA6 (561-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use

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  • Specifications

    Specifications

    NP_001073917.2
    Pharma and biopharma, protein assays and analysis, target and lead identification and validation
    EPHA6 Recombinant Human Protein
    >70% by SDS-PAGE
    –68 to –85°C
    1 Each
    EPHA6 Recombinant Human Protein
    Kinase assay
    EPHA6 Recombinant Human Protein
    Human
    0.1mg/mL
    77kDa
    7.5
    10μg
    For research use only. Not for use in diagnostic procedures
    EPA6, FLJ35246, PRO57066, DKFZp434C1418
    EPHA6 was pre-diluted in enzyme dilution buffer and assayed in 5mM MOPS (pH 7.2), 2.5mM β-glycerol-phosphate, 4mM MgCl2, 2.5mM MnCl2, 0.4mM EDTA, 1mM EGTA, 0.05mM DTT, with 50μM ATP, trace [33P]-γ-ATP and 200μg/mL poly [Glu, Tyr] 4:1 substrate for 15 min.s at 30°C
    Amino acids 561-end
    10nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C
    GST Tag
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