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Epstein Barr Virus Antibody Cocktail, Invitrogen™

Produktkod. 11384583
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Kvantitet:
500 μL
Förpackningsstorlek:
500µL
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11384583 500 μL 500µL
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Produktkod. 11384583 Leverantör Invitrogen Leverantörsnummer MA512172

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Antibody Cocktail

MA5-12172 targets Epstein-Barr Virus in IHC (P) applications and shows reactivity with Bacteria samples. The MA5-12172 immunogen is eBV-encoded recombinant latent membrane protein.

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen Epstein Barr Virus
Användningsområden Immunohistochemistry (Paraffin)
Klassificering Cocktail
Klona CS1, CS2, CS3, CS4, CS2, CS3, CS4
Koncentration Conc. Not Determined
Konjugera Unconjugated
Formulering tissue culture supernatant with 0.09% sodium azide
Gene Alias EBV
Värd art Mouse
Immunogen EBV-encoded recombinant latent membrane protein
Kvantitet 500 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Målarter Virus
Innehåll och lagring 4° C
Produkttyp Antibody
Form Liquid
Isotyp IgG1 κ
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