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Invitrogen™ Equine IL-4, Recombinant Protein

Recombinant Protein

Brand:  Invitrogen™ REIL4I

Additional Details : Weight : 0.80000kg

Product Code. 11818771

  • 3265.00 SEK / 20µg
Estimated Shipment: 16-04-2024
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Description

Description

Equine IL-4 Recombinant Protein, REIL4I, from Invitrogen.

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4. Reconstitute with 0.5 mL of distilled or deionized water. For dilution, use a buffer containing carrier protein, e.g. PBS with 1% BSA or a neutral media containing 10% FCS and freeze in aliquots at -70°C. The biological activity of recombinant equine IL-4 was determined by measuring the proliferation of TF-1 cells. The ED50 (or 1 unit of activity) for this effect in our laboratories typically falls into the range of 20 - 50ng/mL. Ref: Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. Mature equine IL-4 was expressed in Pichia pastoris, X-33. GenBank™ Accession &Num; P42202, amino acids 24 - 132. For protein verification, the expressed protein was N-terminal sequenced and begins with the following 10 amino acids: CKYDITLQEI. Reconstitute with 0.5 mL of distilled water.
Specifications

Specifications

P42202
PBS with no preservative
Equine IL-4
Yeast
RUO
Equine IL-4
Equine
Eq
Recombinant
Recombinant
ELISA, Immunoprecipitation, Western Blot
100034225
20μg
4°C
Equine Interleukin 4 IL4
IL4
Unconjugated
Yeast
Lyophilized
purified
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