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  6. Epredia™ Lab Vision™ Estrogen Receptor Ab-12, Mouse Monoclonal Antibody

Epredia™ Lab Vision™ Estrogen Receptor Ab-12, Mouse Monoclonal Antibody

Produktkod. 12601297 Handla allt Epredia Produkter
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Kvantitet:
100 μL
500 μL
1 mL
7 mL
Form:
Concentrated
Prediluted
Förpackningsstorlek:
100µL
1ml
500µL
7ml
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Produktkod. Kvantitet Form unitSize
12601297 100 μL Concentrated 100µL
12611297 500 μL Concentrated 500µL
12691287 1 mL Concentrated 1ml
12681287 7 mL Prediluted 7ml
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Produktkod. 12601297 Leverantör Epredia™ Leverantörsnummer MS391S0

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Beskrivning

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: 6F11

Isotype: IgG1

Species Reactivity: Human and Rat. Others not known.

Immunogen: Recombinant full-length estrogen receptor protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY

Specifikationer

Antigen Estrogen Receptor Ab-12
Användningsområden Immunoprecipitation
Klassificering Monoclonal
Klona 6F11
Konjugera Unconjugated
Värd art Mouse
Immunogen Recombinant full length estrogen receptor protein
Reningsmetod MCF-7 cells, breast CA
Kvantitet 100 μL
Regulatorisk status RUO
Forskningsdisciplin Steroids Hormones and Growth Factors
Primär eller sekundär Primary
Målarter Human, Rat
Form Concentrated
Isotyp IgG1
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