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Invitrogen™ ETV1 Monoclonal Antibody (1C8B6)

Beskrivning
MA5-15461 targets ETV1 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15461 immunogen is purified recombinant fragment of ETV1 (aa1-191) expressed in E. Coli..
ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.
Specifikationer
Specifikationer
| Antigen | ETV1 |
| Användningsområden | ELISA, Western Blot |
| Klassificering | Monoclonal |
| Klona | 1C8B6 |
| Koncentration | Conc. Not Determined |
| Konjugera | Unconjugated |
| Formulering | ascites with 0.03% sodium azide |
| Gen | Etv1 |
| Genaccessionsnr. | P50549 |
| Gene Alias | DKFZp781L0674; Er81; ets related protein 81; ETS transcription factor Er81; ETS translocation variant 1; ets variant 1; ets variant gene 1; ETS variant transcription factor 1; ets-related protein 81; Etsrp81; Etv1; MGC104699; MGC120533; MGC120534; MGC137631 protein |
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Produkttitel
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