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Invitrogen™ Factor X/Xa (Calcium-dependent) Monoclonal Antibody (CaFX-50)
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Produktkod. 15303931
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Kvantitet:
200 μg
Förpackningsstorlek:
200µg
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15303931 200 μg 200µg
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Produktkod. 15303931 Leverantör Invitrogen™ Leverantörsnummer MA517643

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Beskrivning

Mouse Monoclonal Antibody

This antibody is specific for Human Platelet Factors X and Xa in the presence of 5-10 mM CaCl2.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
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Specifikationer

Antigen Factor X/Xa (Calcium-dependent)
Användningsområden ELISA, Western Blot
Klassificering Monoclonal
Klona CaFX-50
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering PBS with 0.02% sodium azide
Gen F10
Genaccessionsnr. P00742
Gene Alias Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Gensymboler F10
Värd art Mouse
Immunogen Human Factor X purified from the supernatant of thrombin activated platelets.
Reningsmetod Protein G
Kvantitet 200 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 2159
Målarter Human
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotyp IgG1
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Produkttitel
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