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Invitrogen™ Factor X/Xa Polyclonal Antibody
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Produktkod. 11518830
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Kvantitet:
1 mg
Förpackningsstorlek:
1mg
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Produktkod. 11518830 Leverantör Invitrogen™ Leverantörsnummer PA143047

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Sheep Polyclonal Antibody

PA1-43047 detects Factor X in human samples. PA1-43047 has successfully been used in Western blot and ELISA applications. PA1-43047 was derived from human factor X.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen Factor X/Xa
Användningsområden ELISA, Western Blot
Klassificering Polyclonal
Koncentration 11 mg/mL
Konjugera Unconjugated
Formulering 50% water with 50% glycerol and no preservative
Gen F10
Genaccessionsnr. P00742
Gene Alias Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Gensymboler F10
Värd art Sheep
Immunogen Human Factor X.
Reningsmetod SDS-PAGE
Kvantitet 1 mg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 2159
Målarter Human
Innehåll och lagring -20°C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Liquid
Isotyp IgG
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Produkttitel
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