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Fenebrutinib, MedChemExpress

Produktkod. 16490398
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Produktkod. 16490398 Leverantör Medchem Express Leverantörsnummer HY19834

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Description

MedChemExpress Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with Kis of 0.91 nM, 1.6, 1.3, 12.6, and 3.4 nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research.

Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with Kis of 0.91 nM, 1.6, 1.3, 12.6, and 3.4 nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research.

Specifications

Kemiskt namn eller material Fenebrutinib
CAS 1434048-34-6
Färg Off-White
Anteckningar om renhetsgrad Research
Molekylformel C37H44N8O4
Kvantitet 5 mg
Synonym GDC-0853
Löslighetsinformation DMSO : ≥ 23 mg/mL (34.60 mM)
LEDER O=C1C(NC(C=C2)=NC=C2N3CCN(C4COC4)C[C@@H]3C)=CC(C5=CC=NC(N6C(C7=CC(CC(C)(C)C8)=C8N7CC6)=O)=C5CO)=CN1C
Molekylvikt (g/mol) 664.8
Formel vikt 664.8
Procent renhet 98.06%
Kvalitet Research
Fysisk form Solid
För användning med (applikation) Cancer-Kinase/protease
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Research purposes only

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