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Eurofins DiscoverX Fes/Fps Protein, Active
Beskrivning
The cyclin-dependent kinases (CDKs), are a family of serine threonine protein kinases, that control the cell division cycle. In mammals, nine different CDKs (cdk 1 to cdk 9) have been identified. CDKs are regulated on various levels including binding of proteins (cyclins, inhibitors, and assembly factors), protein degradation, transcriptional control, localization, and multiple phosphorylations. This leads to timely regulation of CDK activity, allowing progression from one cell cycle phase to the next. The cdk2 promotes the G1/S trasition and progression through the S phase when bound to specific cyclins (E and A). Recent evidences indicate that CDK2 is involved in cell cycle independent functions such as DNA damage repair.
GenBank X06292
Specifikationer
Specifikationer
| Formulering | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molekylvikt (g/mol) | 98 kDa |
| Kvantitet | 10 μg |
| Art | Human |
| Rekombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Uttryckssystem | Recombinant enzyme expressed in Sf21 insect cells |
| Proteinform | Truncated |
| Renhet eller kvalitetsklass | ≥57% |
| Protein | Fes/Fps, active |
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