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Invitrogen™ Human FGR, His Tag Recombinant Protein

Produktkod. 11519286
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Kvantitet:
10 μg
Förpackningsstorlek:
10µg
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For Research Use Only. All usage must comply with product instructions.

Produktkod. 11519286

Brand: Invitrogen™ P3041

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Denna artikel kan inte returneras. Se returpolicy

For Research Use Only. All usage must comply with product instructions.

Beskrivning

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

FGR is a SRC-related kinase present in hematopoietic cells. FGR signals within multiple pathways including within the integrin pathway and downstream of chemokine and cytokine receptors. This protein contains N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P09769
Koncentration See Label
För användning med (applikation) Kinase Assay
Formulering 20mM tris with 50% glycerol, 0.05mM EDTA, 0.05% NP-40, 100mM NaCl, 1mM DTT and no preservative; pH 7.5
Gen-ID (Entrez) 2268
Molekylvikt (g/mol) 62 kDa
Namn Human FGR, His Tag
pH-intervall 7.5
Reningsmetod Purified
Kvantitet 10 μg
Förvaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias c-fgr; c-fgr protooncogene; c-src2; c-src-2 proto-oncogene; EC 2.7.10.2; feline Gardner-Rasheed sarcoma viral oncogene; feline Gardner-Rasheed sarcoma viral oncogene homolog; FGR; FGR protein; FGR proto-oncogene, Src family tyrosine kinase; FLJ43153; Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; MGC75096; OTTHUMP00000003603; OTTHUMP00000003604; p55c-fgr; p55-c-fgr protein; p55-Fgr; p58c-Fgr; p58-Fgr; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase FGR; SRC2; Tyrosine-protein kinase Fgr; v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog
Vanligt namn FGR
Gensymbol FGR
KinaseFamily SRC Kinase Family
Produkttyp Protein
Konjugera Unconjugated
Art Human
Rekombinant Recombinant
Protein Tag His-tag
Sekvens Full length
Innehåll och lagring -80°C, Avoid Freeze/Thaw Cycles
Analysinträde Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group Tyrosine Kinases
Frakt skick Dry Ice
Systemkompatibilitet LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate
Taggposition C-Terminal
Målinträde FGR
Target Gene Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
Uttryckssystem Insect cells
Proteinfamilj Kinases & Inhibitors
Proteinform Full Length, Recombinant, Cytoplasmic
Form Liquid
Protein subtyp Cytoplasmic Tyrosine Kinases
Forskningskategori Signal Transduction
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