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FIS1 Rabbit anti-Human, Mouse, Porcine, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen FIS1
Concentration 0.33 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16887683
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Proteintech
10956-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 25-04-2024
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16877683
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Proteintech
10956-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 25-04-2024
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Description

Description

This antibody was raised against the full-length of human Fis1 protein, and recognizes endogenous Fis1 protein in various lysates.

Fis1, a 17KDa integral membrane protein, is a novel member of mitochondrial fission machinery. It consists of a central leucine-zipper domain, a coiled-coil region, a tetratricopeptide repeat domain and a C-terminal transmembrane domain. It is a human orthologue of Fis1p (S.cerevisiae) and is localized in the outer mitochondrial membrane. Fis1 acts as a pro-apoptotic factor and plays a vital role in the regulation of mitochondrial fission. It interacts with DLP1 and Mdv1p and facilitates Dnm1p recruitment to the functional fission complex, thereby inducing apoptosis. Role of Fis1 has also been implicated in growth and division of peroxisomes. Loss of Fis1 inhibits apoptosis and results in elongation of mammalian mitochondria.
Specifications

Specifications

FIS1
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunofluorescence, Immunocytochemistry
Unconjugated
Rabbit
Mouse, Human, Porcine, Rat
P84817, Q9CQ92, Q9Y3D6
100622909, 288584, 51024, 66437
FIS1 Fusion Protein Ag1409
Primary
-20°C
FIS1
0.33 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CGI 135, FIS1, FIS1 homolog, hFis1, TPR repeat protein 11, TTC11
Fis1
IgG
Antigen Affinity Chromatography
Antibody
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