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![FLT3 [D835Y] Recombinant Human Protein, Invitrogen™ 10μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
FLT3 [D835Y] Recombinant Human Protein, Invitrogen™
FLT3 [D835Y] Recombinant Human Protein
Brand: Invitrogen PV3967
Additional Details : Weight : 0.00945kg
Description
FLT3 is a tyrosine protein kinase that is a member of the growth factor receptor tyrosine kinase family. The FLT3 D835Y mutant is a drug resistant form of FLT3.Specifications
| NP_004110, D835Y | |
| Pharma and Biopharma, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 48.6kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| FLT3 D835Y, FLK2, STK1, CD135 | |
| FLT3 D835Y was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL Abl1 peptide substrate (EAIYAAPFAKKK) and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| Amino acids 564-958; D835Y | |
| 7,160nmoles of phosphate transferred to Abl1 peptide substrate (EAIYAAPFAKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2μg/mL | |
| His Tag | |
| Kinase and inhibitors | |
| 65% by SDS-PAGE |
| 0.2mg/mL | |
| 2322, 4790 | |
| FLT3 [D835Y] Recombinant Human Protein | |
| –80°C | |
| 1 Each | |
| FLT3 [D835Y] Recombinant Human Protein | |
| PDGFR | |
| FLT3 [D835Y] Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| Receptor tyrosine kinases |
For Research Use Only. Not for use in diagnostic procedures.