missing translation for 'onlineSavingsMsg'
Läs mer
  1. Home
  2. Products
  3. Proteinanalysreagenser
  4. Bioaktiva små molekyler
  5. 18797136

Tocris Bioscience™ FMF-04-159-2
GREENER_CHOICE

Produktkod. 18797136
Change view
Klicka för att se tillgängliga alternativ
Kvantitet:
10 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Produktkod. Kvantitet
18797136 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denna artikel kan inte returneras. Se returpolicy
Produktkod. 18797136 Leverantör Tocris Bioscience™ Leverantörsnummer 7158/10

Please to purchase this item. Need a web account? Register with us today!

Denna artikel kan inte returneras. Se returpolicy

Beskrivning

Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members

FMF-04-159-2 is a potent inhibitor of CDK14 and CDK16 (IC50 = 40 nM for CDK14 in cellular BRET assay; IC50 values are 88 and 10 nM for CDK14 and CDK16 in kinase activity inhibition assay, respectively). Inhibits other TAIRE kinase family members at 1 μM (CDK17 and CDK18). Also binds CDK2 (IC50 = 256 nM). Displays covalent binding of CDK14, with binding sustained after washout. Causes cell cycle arrest at G2/M in cancer cell lines. Reversible control FMF-04-159-R (Cat. No. 7159) also available.
TRUSTED_SUSTAINABILITY

Specifikationer

Kemiskt namn eller material N-[1-[[3-[[(2 E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6- trichlorobenzoyl)amino]-1 H-pyrazole-3-carboxamide
CAS 2364489-81-4
Kvantitet 10 mg
Mål Cyclin-dependent Kinase Inhibitors
Molekylformel C28H30Cl3N7O5S
Renhet 0.98
Produkttitel
Välj ett problem

Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.