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FOXC1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 55365-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16826835

  • 3313.85 SEK / 150µL
Estimated Shipment: 07-12-2021

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Description

Description

This antibody is specific to FOXC1. Phosphorylation modification of Foxc1 protein may be responsible for the larger molecular weight of detection compared with theoretical molecular weight.

FOXC1 is a protein belonging to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this protein is not known, however, it plays a role in the regulation of FGF19-FGFR4-MAPK pathway to promote both the development and maintece of anterior segment structures within the eye. Mutations in this gene cause various glaucoma, iridogoniodysgenesis anomaly, Peters anomaly that includes central corneal leukoma, absence of the posterior corneal stroma and Descemetmembrane and Axenfeld-Rieger anomaly characterized by posterior corneal embryotoxon, iris adhesion to the Schwalbe line, hypertelorism, hypoplasia of the malar bones, congenital absence of some teeth and mental retardation.
Specifications

Specifications

FOXC1
0.74 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q12948, Q61572
ARA, FKHL7, forkhead box C1, Forkhead box protein C1, Forkhead related protein FKHL7, FOXC1, FREAC 3, FREAC3, IGDA, IHG1, IRID1, RIEG3
Rabbit
IgG
150 μL
-20°C
Primary
17300, 2296
Immunoprecipitation, Western Blot
Unconjugated
FOXC1
Liquid
Foxc1
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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