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FOXP3 Monoclonal Antibody (PCH101), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-4776-41

1249.39 SEK valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.23750kg

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Product Code. 15560217

  • 1874.00 SEK / 25 tests
Estimated Shipment: 07-05-2024
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Description

Description

Description: eBioscience offers a panel of monoclonal antibodies to different epitopes of human Foxp3, providing useful tools for investigating the complete expression pattern of Foxp3 at the protein level, and discerning the precise subsets of Foxp3^+ cells. The PCH101 antibody reacts with the amino terminus of human foxp3 protein also known as FORKHEAD BOX P3, SCURFIN, and JM2; cross reactivity of this antibody to other proteins has not been determined. Foxp3, a 49-55 kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in 'scurfy' (sf) mice. Constitutive high expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells. Intracellular staining of human peripheral blood mononuclear cells (PBMCs) with PCH101 antibody using the anti-human Foxp3 Staining Set and protocol reveals approximately 0.5-4% of lymphocytes staining, with the majority of staining occurring in the CD25^bright population. This is subject to donor variability. PCH101 crossreacts with rhesus, chimpanzee and cynomolgus. We recommend the use of CD4 (OKT4, cat. 11-0048, or RPA-T4, cat. 11-0049, depending on the species) and CD25 (BC96, cat. 17-0259). Applications Reported: This PCH101 antibody has been reported for use in intracellular staining followed by flow cytometric analysis.

FOXP3 Monoclonal antibody specifically detects FOXP3 in Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey samples. It is validated for Flow Cytometry.
Specifications

Specifications

FOXP3
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Q6U8D7, Q9BZS1
Foxp3
Affinity chromatography
RUO
102120882, 50943, 574303, 740909
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
PCH101
Alexa Fluor 488
Foxp3
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
Rat
25 Tests
Primary
Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey
Antibody
IgG2a κ
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