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Invitrogen™ Human FRAP1 (mTOR), GST Tag Recombinant Protein

Produktkod. 10012913
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Kvantitet:
10 μg
Förpackningsstorlek:
Varje
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For Research Use Only. All usage must comply with product instructions.

Produktkod. 10012913

Brand: Invitrogen™ PV4753

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Denna artikel kan inte returneras. Se returpolicy

For Research Use Only. All usage must comply with product instructions.

Beskrivning

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™.

FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P42345
Koncentration See Label
För användning med (applikation) Kinase Assay
Formulering 50mM tris with 150mM NaCl, 2mM DTT, 0.1% polysorbate 20, 50% glycerol, 0.5mM EDTA and no preservative; pH 7.5
Gen-ID (Entrez) 2475
Molekylvikt (g/mol) 163.9 kDa
Namn Human FRAP1 (mTOR), GST Tag
pH-intervall 7.5
Reningsmetod Purified
Kvantitet 10 μg
Förvaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias 2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS
Vanligt namn mTOR
Gensymbol MTOR
KinaseFamily PIKK Kinase Family
Protein Längd 1360-2549
Produkttyp Protein
Konjugera Unconjugated
Art Human
Rekombinant Recombinant
Protein Tag GST-tag
Sekvens 1360-2549
Innehåll och lagring -80°C, Avoid Freeze/Thaw Cycles
Analysinträde Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group Ser⁄Thr Kinases: Atypical
Frakt skick Dry Ice
Systemkompatibilitet LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
Målinträde mTOR, FRAP1
Target Gene FK506 binding protein 12-rapamycin associated protein 1
Uttryckssystem Insect cells
Proteinfamilj Kinases & Inhibitors
Proteinform Recombinant, Catalytic
Form Liquid
Protein subtyp Serine/Threonine Kinases
Forskningskategori Signal Transduction, Drug Development, Oncology
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