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Invitrogen™ Human FYN A, GST Tag Recombinant Protein

Human FYN A, GST Tag Recombinant Protein

4230.00 SEK - 64700.00 SEK

Specifications

Gene Alias SLK, SYN, MGC45350
Species Human
Recombinant Recombinant
Protein Tag GST Tag
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15428983
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Invitrogen™
PV6346
10μg
4230.00 SEK
10µg
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Estimated Shipment: 16-04-2024
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15438983
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Invitrogen™
PV6347
100μg
14440.00 SEK
100µg
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Estimated Shipment: 16-04-2024
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15448983
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Invitrogen™
PV6348
1mg
64700.00 SEK
1mg
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Estimated Shipment: 16-04-2024
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Description

Description

Fyn has been shown to phosphorylate Dab1, an intracellular adaptor protein that interacts with amyloid precursor protein (APP) and apoE receptor 2 (apoEr2). The interaction of Fyn and Dab1 regulates the phosphorylation, trafficking, and processing of APP and apoEr2. Fyn expression has been shown to be significantly increased in Chronic Myelogenous Leukemia (CML). Knockdown of Fyn with shRNA slows leukemia cell growth, inhibits clonogenicity, and leads to increased sensitivity to imatinib.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

SLK, SYN, MGC45350
Human
Recombinant
GST Tag
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Documents

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