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GAD65 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20746-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16840315

  • 3313.85 SEK / 150µL
Estimated Shipment: 03-10-2022
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Description

Description

The antibody is specific to GAD2.

GAD65 (glutamic acid decarboxylase-65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.
Specifications

Specifications

GAD65
Polyclonal
Unconjugated
GAD2
GAD 65, GAD2, GAD65, Glutamate decarboxylase 2
Rabbit
Antigen Affinity Chromatography
RUO
14417, 24380, 2572
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry
0.55 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P48320, Q05329, Q05683
Gad2
Peptide
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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