missing translation for 'onlineSavingsMsg'
Learn More

GARP Monoclonal Antibody (YGIC86), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

1444.00 SEK - 3615.00 SEK

Specifications

Antigen GARP
Clone YGIC86
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15269359
View Documents Promotion Details
Affymetrix eBioscience
12-9891-80
25 μg
1444.00 SEK
25µg
View alternative products
Save Up to 
»
In Stock
to see stock.
Please to purchase this item. Need a web account? Register with us today!
15279359
View Documents Promotion Details
Affymetrix eBioscience
12-9891-82
100 μg
3615.00 SEK
100µg
View alternative products
Save Up to 
»
In Stock
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The YGIC86 monoclonal antibody reacts with mouse Glycoprotein A Repetitions Predomit (GARP, also known as Lrrc32 or Garpin). GARP is an approximately 80 kDa glycoprotein that is expressed on the cell surface. Using northern blot, RT-PCR or microarray analyses, the expression of GARP has been reported in placenta, lung, kidney, heart, ovary, liver, skeletal muscle, and pancreas. Protein expression has been observed on megakaryocytes, platelets and activated regulatory T (Treg) cells. The expression of GARP on Treg cells has been reported to be necessary for the suppressive function of Treg cells, possibly related to its role as a cell surface receptor for LAP/TGF beta. When looking for expression of GARP on platelets, it is recommended to use the Foxp3 Staining Buffer Set (cat. 00-5523) to fix the platelets before staining with this YGIC86 monoclonal antibody. Fixation/permeabilization is not necessary when staining Treg cells. YGIC86 does not cross-react to rat GARP. Applications Reported: This YGIC86 antibody has been reported for use in flow cytometric analysis. Applications Tested: This YGIC86 antibody has been tested by flow cytometric analysis of stimulated mouse spleen cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.

GARP, also known as leucine rich repeat containing 32, is a type I membrane protein with twenty-two leucine-rich repeats and a short intracytoplasmic region. GARP was identified based on the analysis of gene expression profiling of Treg and Th cells following TCR stimulation. Since GARP is expressed in CD4+, CD25+, FoxP3+ cells (Tregs), it may be a candidate for cell surface marker for Treg cells.
Specifications

Specifications

GARP
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32
LRRC32
Primary
4° C, store in dark, DO NOT FREEZE!
LRRC32
YGIC86
Flow Cytometry
PE
Rat
Mouse
G3XA59
434215
IgG2a κ
Affinity chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.