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GCK Rabbit anti-Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19666-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16879134

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
Specifications

Specifications

GCK
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P17712, P52792
GCK, GK, GLK, Glucokinase, glucokinase (hexokinase 4), Hexokinase 4, Hexokinase D, Hexokinase type IV, HHF3, HK IV, HK4, HKIV, HXKP, MODY2
Rabbit
IgG
20 μL
-20°C
Primary
103988, 24385
Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Gck
Liquid
Gck
GCK Fusion Protein Ag8116
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Mouse
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