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DPM2, Goat, Polyclonal Antibody, Abnova™
Beskrivning
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq
Specifikationer
Specifikationer
| Antigen | DPM2 |
| Användningsområden | ELISA |
| Klassificering | Polyclonal |
| Koncentration | 0.5 mg/mL |
| Konjugera | Unconjugated |
| Beskrivning | Goat polyclonal antibody raised against synthetic peptide of DPM2. |
| Utspädning | ELISA (1:8000) The optimal working dilution should be determined by the end user. |
| Formulering | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gen | DPM2 |
| Genaccessionsnr. | NP_003854.1 |
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For Research Use Only
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