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Invitrogen™ GPR37 Monoclonal Antibody (436923)

Produktkod. 30535583
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Kvantitet:
100 μg
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Produktkod. Kvantitet
30535583 100 μg
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Produktkod. 30535583 Leverantör Invitrogen™ Leverantörsnummer MA561440

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Beskrivning

Mouse Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen GPR37
Användningsområden Flow Cytometry
Klassificering Monoclonal
Klona 436923
Koncentration 0.5 mg/mL
Konjugera Unconjugated
Formulering PBS with 5% trehalose and no preservative
Gen GPR37
Genaccessionsnr. O15354
Gene Alias AI848630; EDNRBL; endothelin B receptor-like protein 1; ETBR-LP-1; G protein-coupled receptor 37; G protein-coupled receptor 37 (endothelin receptor type B-like); Gpcr/cns1; Gpr37; G-protein coupled receptor 37; G-protein coupled receptor CNS1; hET(B)R-LP; Het-b-r-lp; Pael receptor; PAELR; Pael-R; parkin-associated endothelin B-like receptor; Parkin-associated endothelin receptor-like receptor; probable G-protein coupled receptor 37; prosaposin receptor GPR37
Gensymboler GPR37
Värd art Mouse
Immunogen NS0 mouse myeloma cell line transfected with human GPR37, Ala27-Cys613.
Reningsmetod Protein A/G
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 2861
Målarter Human
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Lyophilized
Isotyp IgG2a
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