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GRM8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1236.20 SEK - 3313.85 SEK

Specifications

Antigen GRM8
Concentration 0.37 mg/mL
Applications Immunohistochemistry (Paraffin)
Conjugate Unconjugated
Format Liquid
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16868284
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Proteintech
18224-1-AP-150UL
150 μL
3313.85 SEK
150µL
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Estimated Shipment: 31-01-2022
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16878284
View Documents Promotion Details
Proteintech
18224-1-AP-20UL
20 μL
1236.20 SEK
20µL
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Estimated Shipment: 31-01-2022
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Description

Description

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Specifications

Specifications

GRM8
Immunohistochemistry (Paraffin)
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Polyclonal
-20°C
0.37 mg/mL
Unconjugated
Rabbit
Human, Mouse, Rat
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications