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Tocris Bioscience™ GSK 2606414

Produktkod. 18065402
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Kvantitet:
10 mg
50 mg
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Produktkod. 18065402

Brand: Tocris Bioscience™ 5107/10

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Description

Potent and selective PERK inhibitor; orally bioavailable

GSK 2606414 is a potent and selective protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for PERK over HR1 and PKR. Inhibits thapsigargin-induced PERK phosphorylation in lung carcinoma A549 cells. Attenuates subcutaneous pancreatic human tumor xenograft growth in mice. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Kvantitet 10 mg
Produkttyp GSK 2606414
Renhet >99%
Molekylvikt (g/mol) 451.44
Inhibitorer GSK 2606414

For Research Use Only

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