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GSK-872, MedChemExpress

Produktkod. 16490017
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Produktkod. 16490017 Leverantör Medchem Express Leverantörsnummer HY101872

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MedChemExpress GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury.

GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury.

Specifikationer

Kemiskt namn eller material GSK-872
CAS 1346546-69-7
Färg Off-White
Anteckningar om renhetsgrad Research
Molekylformel C19H17N3O2S2
Kvantitet 50 mg
Löslighetsinformation DMSO : 100 mg/mL (260.76 mM; Need ultrasonic)
LEDER O=S(C1=CC=C2N=CC=C(C2=C1)NC3=CC=C4SC=NC4=C3)(C(C)C)=O
Molekylvikt (g/mol) 383.49
Formel vikt 383.49
Procent renhet 98.0%
Kvalitet Research
Fysisk form Powder
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Research purposes only

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