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GSK2578215A

Potent, selective LRRK2 inhibitor; brain penetrant

1994.21 SEK - 6837.84 SEK

Specifications

Chemical Name or Material 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide
CAS 1285515-21-0
Assay Percent Range >99%
Molecular Formula C24H18FN3O2
Formula Weight Observed MW: 399.42
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Product Code Brand Quantity Price Quantity & Availability  
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Tocris
4629/25
25 mg
6837.84 SEK
25mg
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18065002
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Tocris
4629/5
5 mg
1994.21 SEK
5mg
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Estimated Shipment: 16-08-2024
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Description

Description

Potent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant.
Specifications

Specifications

5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide
>99%
Observed MW: 399.42
1285515-21-0
C24H18FN3O2
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