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Harmine, 98+%

Produktkod. 11359615
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Kvantitet:
250 mg
1 g
Förpackningsstorlek:
1g
250mg
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11359615 250 mg 250mg
11349615 1 g 1g
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Produktkod. 11359615 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer L19068.MD
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Beskrivning

CAS: 442-51-3 | C13H12N2O | 212.25 g/mol

Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.

Solubility
Soluble in DMSO (100 mM), DMF (∼1.5 mg/ml), ethanol (∼1.5 mg/ml), and PBS (pH 7.2, ∼0.25 mg/ml). Insoluble in water.

Notes
Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 442-51-3
Molekylformel C13H12N2O
Molekylvikt (g/mol) 212.25
MDL-nummer MFCD00004958
InChI-nyckel BXNJHAXVSOCGBA-UHFFFAOYSA-N
Synonym harmine, 7-methoxy-1-methyl-9h-pyrido 3,4-b indole, banisterine, leucoharmine, telepathine, yageine, yajeine, 7-methoxy-1-methyl-9h-beta-carboline, 9h-pyrido 3,4-b indole, 7-methoxy-1-methyl, banisterin
PubChem CID 5280953
ChEBI CHEBI:28121
IUPAC-namn 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
LEDER COC1=CC2=C(C=C1)C1=C(N2)C(C)=NC=C1

Specifikationer

Kemiskt namn eller material Harmine
Smältpunkt 262°C to 266°C
Odör Odorless
Kvantitet 250 mg
Beilstein 178813
Merck Index 14,4616
Löslighetsinformation Soluble in DMSO (100 mM),DMF (∽1.5mg/ml),ethanol (∽1.5mg/ml),and PBS (pH 7.2,∽0.25mg/ml). Insoluble in water.
Formel vikt 212.25
Procent renhet ≥98%

RUO – Research Use Only

Produkttitel
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