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Invitrogen™ HCK Polyclonal Antibody

Beskrivning
Immunogen sequence: MGCMKSKFLQ VGGNTFSKTE TSASPHCPVY VPDPTSTIKP GPNSHNSNTP GIREAGSEDI IVVALYDYEA IHHEDLSFQK GDQMVVLEES GEWWKARSLA TRKEGYIPSN YVARVDSLET EEWFFKGISR KDAERQLLAP GNMLGSFMIR DSETTKGSYS LSVRDYDPRQ GDTVKHYKIR TLDNGGFYIS PRSTFSTLQE LVDHYKKGND GLCQKLSVPC.
Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in some forms of leukemia. (HCK Alias: DKFZp686D0638). HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
Specifikationer
Specifikationer
| Antigen | HCK |
| Användningsområden | ELISA, Western Blot, Immunocytochemistry |
| Klassificering | Polyclonal |
| Koncentration | 1.4 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gen | HCK |
| Genaccessionsnr. | P08631 |
| Gene Alias | AI849071; B cell/myeloid kinase; B-cell/myeloid kinase; BMK; HCK; HCK proto-oncogene, Src family tyrosine kinase; Hctk; Hematopoietic cell kinase; hemopoietic cell kinase; hemopoietic cell tyrosine kinase; JTK9; p56Hck; p56-HCK; p56-HCK/p59-HCK; p59Hck; p59-HCK/p60-HCK; p61Hck; tyrosine-protein kinase HCK |
| Gensymboler | HCK |
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Produkttitel
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