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Invitrogen™ HGK Polyclonal Antibody

Beskrivning
The antibody detects endogenous levels of total HGK / MAP4K4 protein.
MAP4K4 (HGK) is a serine/threonine kinase which plays an important role in stress-activated MAPK core signaling pathways, the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.
Specifikationer
Specifikationer
| Antigen | HGK |
| Användningsområden | Western Blot, Immunocytochemistry |
| Klassificering | Polyclonal |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gen | MAP4K4 |
| Genaccessionsnr. | O95819, P97820 |
| Gene Alias | 9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK |
| Gensymboler | MAP4K4 |
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Produkttitel
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