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Invitrogen™ Histone H3 Biosimilar Recombinant Monoclonal Antibody
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Produktkod. 30282752
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Kvantitet:
1 mg
100 μg
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Produktkod. Kvantitet
30282752 100 μg
30282477 1 mg
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Produktkod. 30282752 Leverantör Invitrogen™ Leverantörsnummer MA558945

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Beskrivning

Recombinant Monoclonal Antibody

For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term Immunomedics patent anti-Histone H3.

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
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Specifikationer

Antigen Histone H3 Biosimilar
Användningsområden ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance
Klassificering Recombinant Monoclonal
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2
Värd art Human
Reningsmetod Protein A
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Målarter Human
Innehåll och lagring -20°C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Lyophilized
Isotyp IgG1
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