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HLA-A2 Mouse anti-Human, APC, Clone: BB7.2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-9876-42

Additional Details : Weight : 0.23750kg

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Product Code. 15558266

  • 2550.00 SEK / 100 tests


In stock, ready to ship: 1
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Description

Description

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.
Specifications

Specifications

HLA-A2
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P05534
DAQB-90C11.16, FLJ26655, HLAA
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
BB7.2
APC
HLA-A
Liquid
HLA-A
IgG2b, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3105
Videos
SDS
Documents

For Research Use Only.