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HPOB, MedChemExpress
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Description
HPOB is a highly potent and selective inhibitor of HDAC6 with an IC50 of 56 nM. HPOB displays >30 fold less potent against other HDACs. HPOB enhances the effectiveness of DNA-damaging anticancer agents in transformed cells but not normal cells. HPOB does not block the ubiquitin-binding activity of HDAC6.
Specifications
Specifications
| Kemiskt namn eller material | HPOB |
| Fysisk form | Solid |
| CAS | 1429651-50-2 |
| Färg | Pink |
| Kvantitet | 50 mg |
| Anteckningar om renhetsgrad | Research |
| Molekylformel | C17H18N2O4 |
| För användning med (applikation) | Cancer-programmed cell death |
| Löslighetsinformation | DMSO : 50 mg/mL (159.06 mM; Need ultrasonic) |
| LEDER | O=C(N(CCO)C1=CC=CC=C1)CC2=CC=C(C(NO)=O)C=C2 |
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Research purposes only
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