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Invitrogen™ HRD1 Polyclonal Antibody
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Produktkod. 10028649
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Kvantitet:
400 μL
Förpackningsstorlek:
100µg
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Produktkod. Kvantitet unitSize
10028649 400 μL 100µg
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Produktkod. 10028649 Leverantör Invitrogen™ Leverantörsnummer PA512093

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Beskrivning

Rabbit Polyclonal Antibody

HRD1 Polyclonal Antibody for Western Blot, IHC (P), ICC/IF

HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects. HRD1 contains one ring-type zinc finger.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen HRD1
Användningsområden Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Klassificering Polyclonal
Koncentration 1.8 mg/mL
Konjugera Unconjugated
Formulering PBS with 0.09% sodium azide; pH 7.4
Gen SYVN1
Genaccessionsnr. Q86TM6, Q9DBY1
Gene Alias 1200010C09Rik; AW211966; C85322; D530017H19Rik; DER3; E3 ubiquitin-protein ligase synoviolin; HMG-coA reductase degradation 1 homolog; Hrd1; HRD1 protein; KIAA1810; MGC40372; RGD1310488; RING-type E3 ubiquitin transferase synoviolin; Synovial apoptosis inhibitor 1; synovial apoptosis inhibitor 1, synoviolin; synoviolin 1; Syvn1
Gensymboler SYVN1
Värd art Rabbit
Immunogen KLH conjugated synthetic peptide between 586-617 amino acids from the C-terminal region of human SYVN1 (HRD1).
Reningsmetod Size-exclusion - Dialysis, Ammonium sulfate precipitation
Kvantitet 400 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 74126, 84447
Målarter Human, Mouse
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotyp IgG
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