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Invitrogen™ Human Activin A Recombinant Protein
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Kvantitet:
1 mg
Förpackningsstorlek:
1mg
Beskrivning
RP-75637 contains purified recombinant human Inhibin beta A protein with an N-terminal hexahistidine tag. RP-75637 may be used as a positive control in many immunological assays.
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
Specifikationer
Specifikationer
| Tillträdesnummer | P08476 |
| Koncentration | 0.153 mg/mL |
| För användning med (applikation) | Control, Western Blot |
| Formulering | tris HCl with 1 mM EDTA, 50% glycerol and no preservative; pH 8 |
| Gen-ID (Entrez) | 3624 |
| Namn | Human Activin A |
| Kvantitet | 1 mg |
| Källa | E. coli |
| Immunogen | N/A |
| Regulatorisk status | RUO |
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