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Abnova™ Human ALK Partial ORF (NP_004295, 251 a.a. - 350 a.a.) Recombinant Protein with GST-tag at N-terminal
Used for AP, Array, ELISA, WB-Re
4055.00 SEK - 6150.00 SEK
Specifications
| Name | ALK (Human) Recombinant Protein (Q01) |
|---|---|
| Recombinant | Yes |
| For Use With (Application) | Antibody Production, Enzyme-linked Immunoabsorbent Assay, Protein Array, Western Blot (Recombinant protein) |
| Molecular Weight | 36.74kDa |
| Storage Requirements | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16043615
|
Abnova™
H00000238-Q01.25UG |
25 ug |
6150.00 SEK
25µg |
Estimated Shipment: 08-09-2022 Log in to see stock. |
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16033615
|
Abnova™
H00000238-Q01.10UG |
10 ug |
4055.00 SEK
10µg |
Estimated Shipment: 08-09-2022 Log in to see stock. |
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Description
The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5. A recent study shows that the product of the NPM-ALK fusion gene is oncogenic. The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain. These sequences are absent in the product of the transforming NPM-ALK gene. ALK shows the greatest sequence similarity to LTK (leukocyte tyrosine kinase). ALK plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. [provided by RefSeq]
Sequence: DSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWRRIPSEEASQMDLLDGPGAERSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSSpecifications
| ALK (Human) Recombinant Protein (Q01) | |
| Antibody Production, Enzyme-linked Immunoabsorbent Assay, Protein Array, Western Blot (Recombinant protein) | |
| Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Yes | |
| 36.74kDa |