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Invitrogen™ Human APC13 Synthetic Peptide
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Kvantitet:
50 μg
Förpackningsstorlek:
50µg
Beskrivning
APC13 Synthetic Peptide, PEP-1070, from Invitrogen.
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
Specifikationer
Specifikationer
| Gen-ID (Entrez) | 25847 |
| Art | Human |
| Reningsmetod | purified |
| Tillträdesnummer | Q9BS18 |
| Vanligt namn | Human APC13 |
| Koncentration | 200 μg/mL |
| Innehåll och lagring | -20°C |
| Beskrivning | Synthetic Peptide |
| Formatera | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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