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Gibco™ Human APRIL Recombinant Protein, PeproTech®

Produktkod. 30131984 Handla allt Gibco Produkter
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10 x 50 μg
20 x 50 μg
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Produktkod. Kvantitet
30131984 20 x 50 μg
30131761 10 x 50 μg
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Produktkod. 30131984 Leverantör Gibco™ Leverantörsnummer 31010C01M
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Beskrivning

Recombinant Protein

310-10C-01M will be provided as 20 x 50 μg (310-10C-50UG). 310-10C-500 will be provided as 10 x 50 μg (310-10C-50UG). 310-10C-250 will be provided as 5 x 50 μg (310-10C-50UG). 310-10C-100 will be provided as 2 x 50 μg (310-10C-50UG) Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues. *Human APRIL (Catalog Number 310-10C) has replaced Human APRIL (Catalog Number 310-10). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer O75888
För användning med (applikation) Control, Bioactivity
Formatera Lyophilized
Formulering Protein with no preservative
Gen-ID (Entrez) 8741
Molekylvikt (g/mol) 16.3 kDa
Namn Human APRIL
Reningsmetod Purified
Kvantitet 20 x 50 μg
Förvaringskrav -20°C
Regulatorisk status RUO
Endotoxinkoncentration <1 EU/μg
Gene Alias 2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2
Vanligt namn APRIL
Gensymbol TNFSF13
Biologisk aktivitet Determined by its ability to induce NF-kappaB activation in HEK293-NF-kappaB reporter cells transfected with BCMA receptor.
Produkttyp Protein
Konjugera Unconjugated
Rekombinant Recombinant
Sekvens AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL
Innehåll och lagring -20°C
Aktivitet Determined by its ability to induce NF-kappaB activation in HEK293-NF-kappaB reporter cells transfected with BCMA receptor.
Uttryckssystem Insect cells
Form Lyophilized
Renhet eller kvalitetsklass ≥ 95% by SDS-PAGE gel and HPLC analyses.
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