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Invitrogen™ Human ARMET Synthetic Peptide
Beschreibung
This peptide corresponds to 12 amino acids near the amino terminus of human MANF. PEP-0549 can be used as a blocking peptide with polyclonal antibody PA5-20432.
The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Spezifikation
Spezifikation
| Gen-ID (Entrez) | 7873 |
| Art | Human |
| Reningsmetod | purified |
| Tillträdesnummer | P55145 |
| Vanligt namn | ARMET |
| Koncentration | 200 μg/mL |
| Innehåll och lagring | -20°C |
| Beskrivning | Synthetic Peptide |
| Formatera | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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