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Invitrogen™ Human ATP6V0A1 (aa 35-129) Control Fragment Recombinant Protein
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Kvantitet:
100 μL
Beskrivning
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54570 (PA5-54570. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ATP6V0A1 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles.
Specifikationer
Specifikationer
| Tillträdesnummer | Q93050 |
| Koncentration | ≥5.0 mg/mL |
| För användning med (applikation) | Blocking Assay, Control |
| Formulering | 1 M urea, PBS with no preservative; pH 7.4 |
| Gen-ID (Entrez) | 535 |
| Namn | Human ATP6V0A1 (aa 35-129) Control Fragment |
| Kvantitet | 100 μL |
| Regulatorisk status | RUO |
| Gene Alias | a1; AA959968; adenosine triphosphatase; ATP6a1; ATP6N1; ATP6N1A; Atp6v0a1; ATPase H+ transporting lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 (110/160 kDa); ATPase H+ transporting V0 subunit a1; ATPase, H+ transporting, lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 (110/160 kDa); ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1 A (110/116 kD); ATPase, H+ transporting, lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 A (110/160 kDa); ATPase, H+ transporting, lysosomal non-catalytic accessory protein 1 (110/116 kD); ATPase, H+ transporting, lysosomal noncatalytic accessory protein 1 A; ATPase, H+ transporting, lysosomal V0 subunit a; ATPase, H+ transporting, lysosomal V0 subunit a1; Atpv0a1; Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit; H(+)-transporting two-sector ATPase, 116 kDa accessory protein A1; Stv1; V-A; vacuolar adenosine triphosphatase subunit Ac116; vacuolar H+-ATPase subunit; vacuolar proton pump subunit 1; vacuolar proton translocating ATPase 116 kDa subunit A; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1; vacuolar proton-translocating ATPase a1 isoform; vacuolar-type H(+)-ATPase 115 kDa subunit; V-ATPase 116 kDa; V-ATPase 116 kDa isoform a1; V-ATPase 116 kDa subunit; V-ATPase 116 kDa subunit a1; V-ATPase a1; v-H+ATPase subunit a1; Vph1; Vpp1; Vpp-1; V-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a isoform 1; V-type proton ATPase 116 kDa subunit a isoform 1; V-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a1 |
| Vanligt namn | ATP6V0A1 |
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