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Gibco™ Human BMP-4 Recombinant Protein, PeproTech®

Produktkod. 30089089
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Kvantitet:
10 μg
100 μg
2 μg
2 x 500 μg
250 μg
50 μg
500 μg
Förpackningsstorlek:
10µg
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Produktkod. 30089089

Brand: Gibco™ 12005ET01M

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Beskrivning

Recombinant Protein

120-05ET-1MG will be provided as 2 x 500 μg (120-05ET-500UG). PeproTech's E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
TRUSTED_SUSTAINABILITY

Specifications

Tillträdesnummer P12644
För användning med (applikation) Control, Western Blot Control, Bioactivity
Formulering Protein with no preservative
Gen-ID (Entrez) 652
Molekylvikt (g/mol) 23.9 kDa
Namn Human BMP-4
Reningsmetod Purified
Kvantitet 2 x 500 μg
Källa E. coli
Förvaringskrav -20°C
Regulatorisk status RUO
Endotoxinkoncentration <1 EU/μg
Gene Alias BMP; BMP2B; BMP-2B; Bmp2b1; Bmp2b-1; Bmp4; Bmp-4; BOMPR4A; Bone morphogenetic protein; Bone morphogenetic protein 2B; bone morphogenetic protein 4; bone morphogenetic protein 4 preproprotein; DVR4; Dvr-4; MCOPS6; OFC11; ZYME
Vanligt namn BMP4
Gensymbol BMP4
Biologisk aktivitet Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml
Produkttyp Protein
Konjugera Unconjugated
Rekombinant Recombinant
Sekvens KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR
Innehåll och lagring -20°C
Aktivitet Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
Uttryckssystem E. coli
Form Lyophilized
Renhet eller kvalitetsklass ≥ 98% by SDS-PAGE gel and HPLC analyses.
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